Free Radicals in Brain Pathophysiology

Brain photothrombosis and free radicals

Free radicals and brain aging.

We reviewed here the formation of free radicals and its effect physiologically. Studies mentioned above have indicated that free radical/ROS/RNS involvement in brain aging is direct as well as correlative. Increasing evidence demonstrates that accumulation of oxidation of DNA, proteins, and lipids by free radicals are responsible for the functional decline in aged brains. Also, lipid peroxidati...

Free radicals in brain, functions and failures

Free radicals, you can't live with them and you can't live without them. Appreciation is growing that free radicals and related oxidants are ubiquitous and that they are involved in common pathways that lead to tissue damage from a wide variety of insults. Some combination of reactive oxygen species (ROS) and reactive nitrogen species (RNS) are implicated in an array of neuro-degenerative disea...

Prostaglandins and Free Radicals in Brain

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Free radicals in carcinogenesis.

It has become clear since the workshop that free radicals are implicated not only in the promotion phase of carcinogenesis but during initiation as well. Since the workshop, however, despite intriguing trapping studies with Superoxide disimilase. catalase, and Cu-DIPS [copper(II)(3,5-diisopropylsalicylate)2] and generation of OJ using xanthine oxidase, little substantive evidence has been obtai...